Chiotellis E, Stassinopoulou C I, Varvarigou A, Vavouraki H
J Med Chem. 1982 Nov;25(11):1370-4. doi: 10.1021/jm00353a018.
The synthesis, NMR studies, radiochemical labeling with technetium-99m, and tissue-distribution characteristics of some [(thioethyl)amino] carboxylates are described. The 99mTc agents prepared were eliminated either by the urinary of the hepatobiliary system of mice. The excretion route of the 99mTc complexes was influenced by the structure and total charge of the ligands.
描述了一些[(硫代乙基)氨基]羧酸盐的合成、核磁共振研究、用99m锝进行放射性化学标记以及组织分布特征。所制备的99mTc制剂通过小鼠的泌尿系统或肝胆系统排出。99mTc配合物的排泄途径受配体的结构和总电荷影响。
