Nanninga J B, Wu Y, Hamilton B
J Urol. 1982 Oct;128(4):760-3. doi: 10.1016/s0022-5347(17)53177-8.
Intermittent catheterization was used as a means of long-term bladder management in 85 patients with spinal cord injury. Of these patients followup data revealed that 28 (33 per cent) had reflux and/or hydronephrosis. Treatment in 15 patients consisted of increasing the frequency of catheterization to every 4 hours and avoiding high fluid intake during a relative short interval. Sphincterotomy was done in 3 patients, while 10 were placed on an indwelling catheter because of an inability to adapt to or refusal of other forms of treatment. The upper urinary tract changes noted seemed to be related to increased intravesical pressure, either from too long an interval between catheterizations or from marked detrusor hyperreflexia with sphincter obstruction. Close followup seems necessary in these patients.
85例脊髓损伤患者采用间歇性导尿作为长期膀胱管理方法。对这些患者的随访数据显示,28例(33%)出现反流和/或肾积水。15例患者的治疗方法是将导尿频率增加至每4小时1次,并在相对较短的时间段内避免大量饮水。3例患者进行了括约肌切开术,10例因无法适应或拒绝其他治疗方式而留置导尿管。所观察到的上尿路变化似乎与膀胱内压力升高有关,这可能是由于导尿间隔时间过长,或者是由于逼尿肌反射亢进伴括约肌梗阻所致。对这些患者似乎有必要进行密切随访。