Wright E G, Ali A M, Riches A C, Lord B I
Leuk Res. 1982;6(4):531-9. doi: 10.1016/0145-2126(82)90010-8.
Media conditioned by regenerating murine bone marrow cells contain a stimulator of haemopoietic stem cell proliferation. Fractionated cell populations have been examined for production of this stimulatory activity in order to characterize its cellular source. The stimulator is produced by adherent, phagocytic, radioresistant, Thy 1.2-, Fc+ cells in a population concentrated in a density range of 1.064-1.072 g/ml. The results indicate that the producer cells reside in the heterogenous mononuclear phagocytic population of the bone marrow.
由再生的小鼠骨髓细胞调节的培养基含有造血干细胞增殖刺激因子。为了确定其细胞来源,已对分级分离的细胞群体进行了该刺激活性产生情况的检测。该刺激因子由贴壁、吞噬、抗辐射、Thy 1.2阴性、Fc阳性细胞产生,这些细胞集中在密度范围为1.064 - 1.072 g/ml的群体中。结果表明,产生该刺激因子的细胞存在于骨髓的异质性单核吞噬细胞群体中。