Schabel F, Mitterstieler G
Padiatr Padol. 1978;13(4):391-5.
The clinical picture and the laboratory data of 40 patients with anaphylactoid purpura as well as its etiology and pathogenesis are discussed. The clinical expression and the rate of complications does not differ from that described in the literature. 45% of the patients showed renal involvement, three patients had severe glomerulonephritis. Up to now there is a lack of typical laboratory tests to confirm the diagnosis of anaphylactoid purpura. This study suggests neutrophilia and initial creased fibrin/fibrinogen split products in serum and decreased C3 levels are poor prognostic criteria correlating with appearence and severity of a complicating glomerulonephritis.
本文讨论了40例过敏性紫癜患者的临床表现、实验室数据及其病因和发病机制。其临床表现和并发症发生率与文献报道无异。45%的患者出现肾脏受累,3例患有严重肾小球肾炎。目前缺乏确诊过敏性紫癜的典型实验室检查。本研究表明,中性粒细胞增多、血清中纤维蛋白/纤维蛋白原降解产物初始升高以及C3水平降低是与并发肾小球肾炎的出现和严重程度相关的不良预后指标。