Dastugue N, Picheloup F, Sie P, Genestal M, Cathala B, Boneu B
Nouv Presse Med. 1982 Oct 9;11(39):2899-901.
In a retrospective study the mean platelet volume (MPV) was measured in citrated plasma of 16 patients with hypovolaemic or infectious toxic shock. Bone marrow examination was carried out in most cases. Eighty p. cent of the patients had an increase in MPV, and the increase persisted even after thrombocytopenia had regressed. Cytological examination of the bone marrow failed to provide evidence that bone marrow deficiency was a predominant factor in the pathogenesis of thrombocytopenia in any of these patients. In this particular patient population, bone marrow examination should be reserved to those cases where persistent thrombocytopenia coexists with normal MPV.
在一项回顾性研究中，对16例低血容量性或感染性中毒性休克患者的枸橼酸盐血浆进行了平均血小板体积（MPV）测量。多数病例进行了骨髓检查。80%的患者MPV升高，即使血小板减少症消退后该升高仍持续存在。骨髓细胞学检查未能提供证据表明骨髓缺乏是这些患者中任何一例血小板减少症发病机制的主要因素。在这个特定的患者群体中，骨髓检查应仅保留给那些持续性血小板减少症与正常MPV并存的病例。
