糖基扭转角与糖环构象之间并不总是存在相关性。
Correlation between glycosyl torsion angle and sugar ring pucker does not always exist.
作者信息
Low J N, Tollin P, Wilson H R
出版信息
Nucleic Acids Res. 1982 Sep 25;10(18):5599-604. doi: 10.1093/nar/10.18.5599.
Abstract
A survey of the conformational parameters of deoxypyrimidine nucleosides and nucleotides shows that the correlation between glycosyl torsion angle and sugar pucker, which has often been considered to be well-established, does not always exist. This may be of significance when interactions between DNA and other molecules are considered.
摘要
对脱氧嘧啶核苷和核苷酸构象参数的一项调查显示，糖基扭转角与糖环构象之间的相关性（这种相关性常被认为已得到充分确立）并非总是存在。在考虑DNA与其他分子之间的相互作用时，这可能具有重要意义。
相似文献
1
Correlation between glycosyl torsion angle and sugar ring pucker does not always exist.糖基扭转角与糖环构象之间并不总是存在相关性。
Nucleic Acids Res. 1982 Sep 25;10(18):5599-604. doi: 10.1093/nar/10.18.5599.
2
The J-coupling restrained molecular mechanics (JrMM) protocol--an efficient alternative for deriving DNA endocyclic torsion angle constraints. Part I: Correlation of endocyclic torsion angles and vicinal torsion angle phi 1'2'.
J Biomol Struct Dyn. 1996 Apr;13(5):803-14. doi: 10.1080/07391102.1996.10508893.
3
On the conformational dependence of the proton chemical shifts in nucleosides and nucleotides. I. Proton shifts in the ribose ring of pyrimidine nucleosides as a function of the torsion angle about the glycosyl bond.
J Theor Biol. 1977 Mar 7;65(1):171-88. doi: 10.1016/0022-5193(77)90082-0.
4
Stereochemical studies on nucleic acid analogues. I. Conformations of alpha-nucleosides and alpha-nucleotides: interconversion of sugar puckers via O4'-exo.核酸类似物的立体化学研究。I. α-核苷和α-核苷酸的构象：通过O4'-外向型实现糖环构象的相互转化
Biopolymers. 1992 Mar;32(3):249-69. doi: 10.1002/bip.360320306.
5
Quantum-mechanical studies on the conformation of nucleic acids and their constituents.核酸及其组分构象的量子力学研究。
Prog Nucleic Acid Res Mol Biol. 1976;18:215-322. doi: 10.1016/s0079-6603(08)60589-9.
6
Anti-Syn conformational range of pyrimidines with deoxyribofuranose.具有脱氧呋喃核糖的嘧啶的抗突触构象范围。
J Biomol Struct Dyn. 1998 Jun;15(6):1181-94. doi: 10.1080/07391102.1998.10509012.
7
Conformational studies of alpha- and beta-pyrimidine 2'-deoxyribonucleosides in the syn and anti conformation.
Biochim Biophys Acta. 1980 Jul 29;608(2):435-45. doi: 10.1016/0005-2787(80)90189-6.
8
Conformational characteristics of the dimeric subunits of DNA from energy minimization studies. Mixed sugar-puckered dApdA, dApdT, dTpdA, and dTpdT.来自能量最小化研究的DNA二聚体亚基的构象特征。混合糖环构象的dApdA、dApdT、dTpdA和dTpdT。
Biophys J. 1981 Sep;35(3):731-52. doi: 10.1016/S0006-3495(81)84824-2.
9
Conformational analysis of the sugar ring in nucleosides and nucleotides. Improved method for the interpretation of proton magnetic resonance coupling constants.核苷和核苷酸中糖环的构象分析。解释质子磁共振耦合常数的改进方法。
J Am Chem Soc. 1973 Apr 4;95(7):2333-44. doi: 10.1021/ja00788a038.
10
Determination of the DNA sugar pucker using 13C NMR spectroscopy.使用碳-13核磁共振光谱法测定DNA糖的构象。
Biochemistry. 1989 Nov 28;28(24):9372-8. doi: 10.1021/bi00450a018.
引用本文的文献
1
Stacking in RNA: NMR of Four Tetramers Benchmark Molecular Dynamics.RNA中的堆积：四个四聚体的核磁共振基准分子动力学
J Chem Theory Comput. 2015 Jun 9;11(6):2729-2742. doi: 10.1021/ct501025q. Epub 2015 Apr 16.
2
Optimization of an AMBER force field for the artificial nucleic acid, LNA, and benchmarking with NMR of L(CAAU).优化人工核酸 LNA 的 AMBER 力场并用 L(CAAU) 的 NMR 进行基准测试。
J Phys Chem B. 2014 Feb 6;118(5):1216-28. doi: 10.1021/jp408909t. Epub 2014 Jan 24.
3
A comparison of the conformations adopted by some 5-bromovinyl-2'-deoxyuridines and a correlation with their antiviral properties: an X-ray study.某些5-溴乙烯基-2'-脱氧尿苷所采用构象的比较及其与抗病毒特性的相关性：一项X射线研究。
Nucleic Acids Res. 1987 May 26;15(10):4111-21. doi: 10.1093/nar/15.10.4111.
本文引用的文献
1
THE CRYSTAL AND MOLECULAR STRUCTURE OF 5-FLURO-2'-DEOXY-BETA-URIDINE.5-氟-2'-脱氧-β-尿苷的晶体与分子结构
Biophys J. 1964 May;4(3):203-25. doi: 10.1016/s0006-3495(64)86778-3.
2
Left-handed DNA helices.左手DNA螺旋
Nature. 1980 Feb 21;283(5749):743-5. doi: 10.1038/283743a0.
3
Structure of a B-DNA dodecamer: conformation and dynamics.一种B型DNA十二聚体的结构：构象与动力学
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2179-83. doi: 10.1073/pnas.78.4.2179.
4
The crystal structure of a hydrogen bonded complex of deoxyguanosine and 5-bromodeoxycytidine.
Acta Crystallogr. 1965 Jul 10;19(1):125-30. doi: 10.1107/s0365110x65002864.
5
Changes in nucleoside conformation.核苷构象的变化
Nature. 1970 Feb 7;225(5232):545. doi: 10.1038/225545a0.
6
Conservation of conformation in mono and poly-nucleotides.单核苷酸和多核苷酸中构象的保守性。
Nature. 1969 Nov 29;224(5222):886-8. doi: 10.1038/224886a0.
7
Stereochemistry of nucleic acids and their constituents. XVII. Crystal and molecular structure of deoxycytidine 5'-phosphate monohydrate. A possible puckering for the furanoside ring in B-deoxyribonucleic acid.
J Am Chem Soc. 1971 Sep 8;93(18):4565-73. doi: 10.1021/ja00747a038.
8
Conformational analysis of the sugar ring in nucleosides and nucleotides. A new description using the concept of pseudorotation.核苷和核苷酸中糖环的构象分析。一种使用假旋转概念的新描述。
J Am Chem Soc. 1972 Nov 15;94(23):8205-12. doi: 10.1021/ja00778a043.
9
Nucleic acid-mutagen interactions: crystal structure of adenylyl-3',5'-uridine plus 9-aminoacridine.
Nature. 1975 Jan 31;253(5490):324-7. doi: 10.1038/253324a0.
10
Molecular structure of a deoxyribose-dinucleotide, sodium thymidylyl-(5' yields to 3')-thymidylate-(5') hydrate (pTpT), and a possible structural model for polythymidylate.脱氧核糖二核苷酸——胸苷酰基 -（5' 至 3'）-胸苷酸酯 -（5'）水合物（pTpT）的分子结构以及聚胸苷酸的一种可能结构模型。
J Mol Biol. 1976 Nov 15;107(4):601-21. doi: 10.1016/s0022-2836(76)80086-1.
Zotero 插件