糖基扭转角与糖环构象之间并不总是存在相关性。
Correlation between glycosyl torsion angle and sugar ring pucker does not always exist.
作者信息
Low J N, Tollin P, Wilson H R
出版信息
Nucleic Acids Res. 1982 Sep 25;10(18):5599-604. doi: 10.1093/nar/10.18.5599.
Abstract
A survey of the conformational parameters of deoxypyrimidine nucleosides and nucleotides shows that the correlation between glycosyl torsion angle and sugar pucker, which has often been considered to be well-established, does not always exist. This may be of significance when interactions between DNA and other molecules are considered.
摘要
对脱氧嘧啶核苷和核苷酸构象参数的一项调查显示，糖基扭转角与糖环构象之间的相关性（这种相关性常被认为已得到充分确立）并非总是存在。在考虑DNA与其他分子之间的相互作用时，这可能具有重要意义。
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本文引用的文献
1
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Biophys J. 1964 May;4(3):203-25. doi: 10.1016/s0006-3495(64)86778-3.
2
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Nature. 1980 Feb 21;283(5749):743-5. doi: 10.1038/283743a0.
3
Structure of a B-DNA dodecamer: conformation and dynamics.一种B型DNA十二聚体的结构：构象与动力学
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2179-83. doi: 10.1073/pnas.78.4.2179.
4
The crystal structure of a hydrogen bonded complex of deoxyguanosine and 5-bromodeoxycytidine.
Acta Crystallogr. 1965 Jul 10;19(1):125-30. doi: 10.1107/s0365110x65002864.
5
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Conservation of conformation in mono and poly-nucleotides.单核苷酸和多核苷酸中构象的保守性。
Nature. 1969 Nov 29;224(5222):886-8. doi: 10.1038/224886a0.
7
Stereochemistry of nucleic acids and their constituents. XVII. Crystal and molecular structure of deoxycytidine 5'-phosphate monohydrate. A possible puckering for the furanoside ring in B-deoxyribonucleic acid.
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9
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