左手DNA螺旋

Left-handed DNA helices.

作者信息

Arnott S, Chandrasekaran R, Birdsall D L, Leslie A G, Ratliff R L

出版信息

Nature. 1980 Feb 21;283(5749):743-5. doi: 10.1038/283743a0.

Abstract

The synthetic DNA polymerpoly d(GC) . poly d(GC) has been studied by X-ray diffraction of orientated fibres in which it has either the well known (A or B) randed conformations have been observed with poly d(AC) . poly d(GT) and with poly d(As4T) . poly d(As4T), demonstrating that the novel structure is accessible to any DNA segment with an alternating purine-pyrimidine base sequence.

摘要

合成DNA聚合物聚d(GC).聚d(GC)已通过取向纤维的X射线衍射进行了研究，在该研究中，它与聚d(AC).聚d(GT)以及聚d(As4T).聚d(As4T)一样，观察到了众所周知的（A或B）螺旋构象，这表明具有嘌呤 - 嘧啶交替碱基序列的任何DNA片段都可形成这种新结构。