Bodnar P N, Pristupiuk A M
Probl Endokrinol (Mosk). 1982 Sep-Oct;28(5):15-7.
The content of 2,3-diphosphoglycerate (2,3-DPG) was studied in the red blood cells of 145 patients with diabetes mellitus. A significant (P less than 0.001) increase in 2,3-DPG (8.10 +/- 0.42 mc mol/l of red blood cells) was seen in the diabetic patients as compared with that of the healthy subjects (4.50 +/- 0.40 mc mol/l ml of red blood cells). A rice in 2,3-DPG concentration is not dependent on the patients' age, duration, severity and type of the disease. The determination of a 2,3-DPG level maybe used for evaluation of tissue hypoxia in patients with diabetes mellitus.
对145例糖尿病患者的红细胞中2,3 - 二磷酸甘油酸（2,3 - DPG）含量进行了研究。与健康受试者（红细胞中为4.50±0.40微摩尔/升）相比，糖尿病患者的2,3 - DPG显著升高（P小于0.001）（红细胞中为8.10±0.42微摩尔/升）。2,3 - DPG浓度的升高与患者的年龄、病程、病情严重程度及疾病类型无关。测定2,3 - DPG水平可用于评估糖尿病患者的组织缺氧情况。
