Mayor F
Rev Esp Fisiol. 1982;38 Suppl:251-3.
Neonatal anoxia induces a remarkable rise in brain bilirubin levels in the rat. The percentage of rats affected and the bilirubin levels reached are higher between the 3rd and 6th day after the anoxic episode. The accumulation of bilirubin in the brain could reflect the incidence of intracerebral hemorraghes (of different size and localization) caused by anoxia, and can plan an important role in the ethiology of the bilirubin encephalopathy and the neurological damage due to perinatal asphyxia.
新生大鼠缺氧会导致其脑胆红素水平显著升高。在缺氧发作后的第3天至第6天,受影响的大鼠百分比及所达到的胆红素水平更高。脑内胆红素的蓄积可反映缺氧所致不同大小和部位的脑内出血发生率,且在胆红素脑病的病因及围产期窒息所致神经损伤中可能起重要作用。