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血吸虫病:根除还是控制?

Schistosomiasis: eradication or control?

作者信息

Strickland G T

出版信息

Rev Infect Dis. 1982 Sep-Oct;4(5):951-4. doi: 10.1093/clinids/4.5.951.

DOI:10.1093/clinids/4.5.951
PMID:7146732
Abstract

Schistosomiasis cannot be eradicated from the world at this time. However, it can be eradicated from focal areas where major improvements in the standard of living have occurred. In most areas control of biological transmission can be obtained by a systematic use of chemotherapy along with other methods including control of snails and reduction in both water contamination and contact. In some areas, where the prevalence and intensity of infection are very high, the only reasonable objective is control of the disease (although reduction in transmission should be attempted). Disease morbidity correlates with intensity of infection and can probably be reduced with repeated courses of chemotherapy. The appropriate application of a schistosomal vaccine, when it becomes available, will expedite the eradication of this parasite, which infects greater than 200 million people.

摘要

目前,血吸虫病无法在全球范围内被根除。然而,在生活水平有显著提高的重点地区,血吸虫病是可以被根除的。在大多数地区,通过系统地使用化疗以及包括控制钉螺、减少水污染和接触在内的其他方法,可以实现对生物传播的控制。在一些感染率和感染强度非常高的地区,唯一合理的目标是控制疾病(尽管应尝试减少传播)。疾病发病率与感染强度相关,通过重复化疗疗程可能会降低发病率。当血吸虫疫苗可用时,合理应用将加速根除这种感染超过2亿人的寄生虫。

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