Haldimann B
Schweiz Med Wochenschr. 1982 Oct 2;112(40):1366-8.
Magnesium is an important cation for the organism. In the cell, magnesium is a cofactor of numerous enzymatic processes, while in the extracellular compartment it is involved in neuromuscular excitation. Various clinical conditions lead to magnesium deficiency, the symptoms of which are highly protean. However, hypermagnesemia results almost exclusively from increased magnesium intake in patients with reduced glomerular filtration. The consequences of such magnesium intoxication are essentially neuromuscular.
镁是机体重要的阳离子。在细胞内,镁是众多酶促过程的辅助因子,而在细胞外液中,它参与神经肌肉兴奋过程。多种临床情况可导致镁缺乏,其症状多种多样。然而,高镁血症几乎仅由肾小球滤过率降低患者镁摄入增加所致。这种镁中毒的后果主要是神经肌肉方面的。