Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana 141004, India.
Biol Trace Elem Res. 2010 May;134(2):119-29. doi: 10.1007/s12011-009-8465-z. Epub 2009 Jul 24.
Magnesium is the fourth most abundant cation in the body and plays an important physiological role in many of its functions. It plays a fundamental role as a cofactor in various enzymatic reactions involving energy metabolism. Magnesium is a cofactor of various enzymes in carbohydrate oxidation and plays an important role in glucose transporting mechanism of the cell membrane. It is also involved in insulin secretion, binding, and activity. Magnesium deficiency and hypomagnesemia can result from a wide variety of causes, including deficient magnesium intake, gastrointestinal, and renal losses. Chronic magnesium deficiency has been associated with the development of insulin resistance. The present review discusses the implications of magnesium deficiency in type 2 diabetes.
镁是体内第四丰富的阳离子，在许多功能中发挥着重要的生理作用。它作为各种涉及能量代谢的酶反应的辅助因子起着根本作用。镁是碳水化合物氧化中各种酶的辅助因子，在细胞膜葡萄糖转运机制中起着重要作用。它还参与胰岛素的分泌、结合和活性。镁缺乏和低镁血症可由多种原因引起，包括镁摄入不足、胃肠道和肾脏丢失。慢性镁缺乏与胰岛素抵抗的发展有关。本综述讨论了镁缺乏在 2 型糖尿病中的意义。
