达那唑与口服抗凝剂。
Danazol and oral anticoagulants.
作者信息
Small M, Peterkin M, Lowe G D, McCune G, Thomson J A
出版信息
Scott Med J. 1982 Oct;27(4):331-2. doi: 10.1177/003693308202700414.
PMID:7146883
Abstract
A case report of overt bleeding in a young woman on warfarin given the anabolic steroid danazol for menorrhagia is reported. This interaction appears to be poorly recognised and we suggest that when commencing such a treatment the dose of anticoagulant should initially be halved and thereafter tailored to the thrombotest.
摘要
本文报告了一例年轻女性在使用华法林治疗期间，因服用合成代谢类固醇达那唑治疗月经过多而出现明显出血的病例。这种相互作用似乎未得到充分认识，我们建议在开始此类治疗时，抗凝剂剂量应先减半，然后根据凝血试验结果进行调整。
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