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刺梧桐树胶在大鼠体内的代谢研究。

A study of the fate of gum karaya in the rat.

作者信息

Brown P M, Pringuer M A, Anderson M W

出版信息

Toxicol Lett. 1982 Oct;13(3-4):247-51. doi: 10.1016/0378-4274(82)90219-3.

DOI:10.1016/0378-4274(82)90219-3
PMID:7147269
Abstract

Rats were fed a diet containing 5% gum karaya for 24 h and faeces and urine were collected over 72 h. Faeces were examined, after methanolysis, by gas chromatography--mass spectometry and the quantity and monosaccharide composition of the faecal polysaccharide were compared with the dose and original composition of the gum polysaccharide. Gum-derived rhamnose was not found in the urine. Indications of minor quantitative changes in composition but no evidence of extensive degradation or absorption of gum polysaccharide, were found.

摘要

给大鼠喂食含5%刺梧桐树胶的饲料24小时,并在72小时内收集粪便和尿液。粪便经甲醇解后,用气相色谱-质谱法进行检测,并将粪便多糖的数量和单糖组成与树胶多糖的剂量和原始组成进行比较。尿液中未发现源自树胶的鼠李糖。发现有成分轻微定量变化的迹象,但没有证据表明树胶多糖有广泛降解或吸收。

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