Andzhaparidze O G, Boriskin Iu S, Bogomolova N N, Lotte V D
Vopr Virusol. 1982 Sep-Oct;27(5):22-7.
Viral nucleocapsids isolated from cell cultures of human origin (HEp-2 and L-41) persistently infected with mumps virus for 4 years were analysed. In persistent infection, nucleocapsids accumulated in the cells in greater amounts than in primary infection. The synthesis of NP protein of nucleocapsids in persistent infection was approximately 10 times lower than that in primary infection. Morphologically, nucleocapsids in primary infection are rigid linear helical structures whereas in persistent infection they are of convoluted shape, fragmented, and partially or completely despiralized and destructuralized.
对从持续感染腮腺炎病毒4年的人源细胞培养物（HEp-2和L-41）中分离出的病毒核衣壳进行了分析。在持续感染中，核衣壳在细胞中的积累量比初次感染时更多。持续感染中核衣壳NP蛋白的合成比初次感染时低约10倍。从形态学上看，初次感染中的核衣壳是刚性的线性螺旋结构，而在持续感染中它们呈卷曲状、碎片化，部分或完全解螺旋并结构破坏。
