Zakharieva S, Kiriakov A, Zlatarev O, Kavrŭkova Iu, Ankov V
Vutr Boles. 1982;21(4):75-9.
Plasma prolactin level was studied in 92 practically healthy subjects, distributed into three age groups--20-44, 60-74 and 75-90 as well as in 25 patients with hypertonic disease (HD) aged over 60 and 30 subjects with hyperlipoproteinemia. Plasma prolactin was determined radioimmunologically. The results obtained show that plasma prolactin level is not essentially changed with age advancing. A tendency of plasma prolactin reduction in elderly and aged people is observed but the difference versus the control group is statistically insignificant. The females from the young age group, show significantly higher values of prolactin versus the males. In the elderly and aged people, the differences according to sex in prolactin level disappears, most likely due to dying out of ovarian function of the females and reduction of the stimulating effect of estrogens upon prolactin secretion. The patients with hypertonic disease over 60 and the males with hyperlipoproteinemia show a significant elevation of plasma prolactin as compared with the subjects from the control group.
对92名实际健康的受试者进行了血浆催乳素水平研究，这些受试者分为三个年龄组——20 - 44岁、60 - 74岁和75 - 90岁，还包括25名60岁以上的高血压病（HD）患者和30名高脂蛋白血症患者。采用放射免疫法测定血浆催乳素。所得结果表明，血浆催乳素水平不会随年龄增长而发生本质变化。观察到老年人和高龄者血浆催乳素水平有降低趋势，但与对照组相比差异无统计学意义。年轻年龄组的女性催乳素值明显高于男性。在老年人和高龄者中，催乳素水平的性别差异消失，很可能是由于女性卵巢功能衰退以及雌激素对催乳素分泌的刺激作用减弱。60岁以上的高血压病患者和高脂蛋白血症男性患者的血浆催乳素水平与对照组相比显著升高。
