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[兔脑亚细胞组分中磷脂的缩醛磷脂形式]

[Plasmalogen forms of phospholipids in the subcellular fractions of the rabbit brain].

作者信息

Kruglova E E

出版信息

Zh Evol Biokhim Fiziol. 1982 Sep-Oct;18(5):445-9.

PMID:7148219
Abstract

Data are presented on plasmalogen and diacylic forms of phospholipids-phosphatidylethanolamine and phosphatidylcholine-in different parts of the brain, as well as in different subcellular fractions from the brain of rabbits. Studies were made on 4 brain structures (forebrain, midbrain, cerebellum, medulla oblongata) and 5 subcellular fractions (myelin, nuclei, microsomes, mitochondria, synaptosomes). It was shown that among brain structures, the medulla oblongata has the highest plasmalogen content. The latter being also the highest in myelin fraction. Fatty aldehydes and fatty acids of myelinic plasmalogens are most unsaturated. Nuclear fraction is more similar to myelin than other ones. With respect to relative content and plasmalogen composition, microsomal, mitochondrial and synaptosomal fractions differ from myelin and nuclear fractions.

摘要

本文展示了磷脂酰乙醇胺和磷脂酰胆碱这两种磷脂的缩醛磷脂和二酰基形式在兔脑不同部位以及不同亚细胞组分中的数据。对4种脑结构(前脑、中脑、小脑、延髓)和5种亚细胞组分(髓磷脂、细胞核、微粒体、线粒体、突触体)进行了研究。结果表明,在脑结构中,延髓的缩醛磷脂含量最高。在髓磷脂组分中其含量也最高。髓鞘缩醛磷脂的脂肪醛和脂肪酸最不饱和。细胞核组分比其他组分更类似于髓磷脂。就相对含量和缩醛磷脂组成而言,微粒体、线粒体和突触体组分与髓磷脂和细胞核组分不同。

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