Castelli A, Martorana G E, Meucci E, Bonetti G
Acta Vitaminol Enzymol. 1982;4(3):189-96.
Human peripheral leukocytes from healthy donors have been isolated by means of a suitable separation method to obtain a high yield of lymphocytes and granulocytes with a very low contamination of platelets and red blood cells. Mononuclear cells so purified contain more than double amounts of vitamin C than polymorphonuclear cells. The difference between lymphocytes and granulocytes content also tends to be larger at increasing vitamin concentrations in total leukocytes. A higher level of vitamin C is displayed by the mononuclear cells obtained from women in respect to men, while no significant difference is found in the polymorphonuclear cells.
通过合适的分离方法从健康供体中分离出人类外周血白细胞，以获得高产率的淋巴细胞和粒细胞，同时血小板和红细胞的污染非常低。如此纯化的单核细胞所含维生素C的量是多形核细胞的两倍多。随着总白细胞中维生素浓度的增加，淋巴细胞和粒细胞含量之间的差异也往往更大。从女性获得的单核细胞中维生素C水平高于男性，而多形核细胞中未发现显著差异。
