Howard L, Ovesen L, Satya-Murti S, Chu R
Am J Clin Nutr. 1982 Dec;36(6):1243-9. doi: 10.1093/ajcn/36.6.1243.
The effect of vitamin E deprivation on the fully developed human nervous system is not known. In children with fat malabsorption from various causes neuropathological and neurological changes have been ascribed to vitamin E deficiency. Herein we described a neurological deficit that occurred in a 64-yr-old man with chronic steatorrhea leading to severe vitamin E deficiency. long-term supplementation with vitamin E resulted in clinical improvement beginning a few months after normalization of his vitamin E status.
维生素E缺乏对发育完全的人类神经系统的影响尚不清楚。在因各种原因导致脂肪吸收不良的儿童中，神经病理学和神经学变化被归因于维生素E缺乏。在此，我们描述了一名64岁男性因慢性脂肪泻导致严重维生素E缺乏而出现的神经功能缺损。长期补充维生素E后，在其维生素E水平恢复正常几个月后开始出现临床改善。
