Weder B, Meienberg O, Wildi E, Meier C
Neurology. 1984 Dec;34(12):1561-5. doi: 10.1212/wnl.34.12.1561.
Fifteen years after onset of a malabsorption syndrome, a 49-year-old man had sensory and oculomotor disorder with marked vitamin E deficiency. After 6 months of treatment with high parenteral doses of vitamin E, the neurologic signs slowly receded, but the patient died of gastrointestinal hemorrhage. Autopsy and sural nerve biopsy showed the changes in both central and peripheral nerves; these changes are considered characteristic of vitamin E deficiency.
在出现吸收不良综合征15年后，一名49岁男性出现感觉和动眼神经障碍，并伴有明显的维生素E缺乏。在用高剂量肠胃外维生素E治疗6个月后，神经体征逐渐消退，但患者死于胃肠道出血。尸检和腓肠神经活检显示中枢和周围神经均有变化；这些变化被认为是维生素E缺乏的特征。
