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1973 - 1974年对二氯vos和噻苯达唑糊剂防治马驹感染西氏类圆线虫的对照试验。

Controlled tests of pastes of dichlorvos and thiabendazole against induced Strongyloides westeri infections in pony foals in 1973-1974.

作者信息

Drudge J H, Lyons E T, Tolliver S C

出版信息

Am J Vet Res. 1982 Sep;43(9):1675-7.

PMID:7149417
Abstract

In 1973-1974, 4 controlled tests were performed in pony foals (n = 17) raised parasite-free and experimentally infected with Strongyloides westeri. Administration of infective larvae by stomach tube in 1 test resulted in low-grade infections and tended to invalidate the test. Intraoral and percutaneous (intra-aural) administration of larvae resulted in suitable test infections for 1 and 2 tests, respectively. A paste formulation of dichlorvos at 36.3 mg/kg of body weight removal from 4 ponies. Treatment of 4 the dosage rate of 44 mg/kg was consistently effective (greater than 99% to 100%) for eliminating intestinal infections of S westeri.

摘要

1973年至1974年,对17匹无寄生虫感染且经实验感染了西氏类圆线虫的小马驹进行了4次对照试验。在1次试验中通过胃管给予感染性幼虫导致轻度感染,这往往使试验无效。经口和经皮(耳内)给予幼虫分别在1次和2次试验中产生了合适的试验感染。以36.3毫克/千克体重的剂量率使用敌敌畏糊剂,可使4匹小马驹体内的寄生虫清除。以44毫克/千克的剂量率进行治疗,对于消除西氏类圆线虫的肠道感染始终有效(大于99%至100%)。

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