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分娩患有先天性心脏传导阻滞的后代后出现的迟发性母体狼疮。

Delayed maternal lupus after delivery of offspring with congenital heart block.

作者信息

Kasinath B S, Katz A I

出版信息

Arch Intern Med. 1982 Dec;142(13):2317. doi: 10.1001/archinte.142.13.2317.

Abstract

An association between maternal connective tissue disease, especially lupus, and congenital complete heart block in the offspring has been recently recognized. In general, maternal lupus is clinically or serologically manifest by the time the infant with heart block is born, although in some cases the appearance of maternal disease may be delayed for some time. Systemic lupus erythematosus occurred in the mother of three children with congenital heart block 16 years after delivery of her first affected child. To our knowledge this represents the longest latency period for the appearance of maternal disease on record.

摘要

母体结缔组织病,尤其是狼疮,与后代先天性完全性心脏传导阻滞之间的关联最近已得到确认。一般来说,在患有心脏传导阻滞的婴儿出生时,母体狼疮在临床上或血清学上已有表现,尽管在某些情况下,母体疾病的出现可能会延迟一段时间。一名患有先天性心脏传导阻滞的三个孩子的母亲,在她第一个患病孩子出生16年后出现了系统性红斑狼疮。据我们所知,这是有记录以来母体疾病出现的最长潜伏期。

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