Saksena S K, Lau I F
Prostaglandins Med. 1978 Sep;1(3):201-6. doi: 10.1016/0161-4630(78)90106-4.
Intrauterine insertion of a Silastic-PVP tube containing 400 microgram PGF2alpha terminated midterm pregnancy in 100 per cent of the animals. Progesterone (2 mg/day) or prolactin (PRL) reversed the abortifacient effect of PGF2alpha. A dose- and duration-related effect of the PRL on PGF2alpha induced termination of pregnancy was evident. The results suggest that PGF2alpha and PRL are antagonistic to each other and multiple doses of PRL are needed to neutralize the luteolytic action of PGF2alpha.
向子宫内植入一根含有400微克前列腺素F2α的硅橡胶-聚乙烯吡咯烷酮管，使100%的实验动物中期妊娠终止。孕酮（2毫克/天）或催乳素可逆转前列腺素F2α的堕胎作用。催乳素对前列腺素F2α诱导的妊娠终止具有剂量和时间相关效应。结果表明，前列腺素F2α和催乳素相互拮抗，需要多次给予催乳素才能中和前列腺素F2α的溶黄体作用。
