在麻醉犬的后肢去传入神经和交叉循环后，对电诱导肌肉工作期间的通气反应。

Ventilatory responses during electrically induced muscular work in anesthetized dogs, after both deafferentation and cross circulation of hindlimbs.

Da-Silva A C, Russo A K, Leite-de-Barros-Neto T, Tarasantchi J, Piçarro I C, Griggio M A

Braz J Med Biol Res. 1982 Jul;15(2-3):153-9.

Abstract

The role of the neural afferent component from moving limbs during exercise hyperpnea has been studied in dogs. The influence of neural and humoral effects was evaluated by dorsal root section and limb cross-circulation. 2. Respiratory minute volume (Ve), frequency (f), tidal volume (VT) and oxygen consumption (VO2) were measured in anesthetized dogs submitted to light electrically-induced exercise (ventral root stimulation of L6 or L7), both before and after deafferentation. 3. In control experiments the increase of respiratory minute volume (Ve) was directly proportional to VO2, and primarily due to changes in frequency. After dorsal root section (L1 to S1), VO2 increased, but no significant changes were observed in the other respiratory parameters. 4. In contrast to the deafferentation experiments, no changes were detected either in Ve or in f during exercise in the cross-circulation experiments. 5. It is concluded that during light exercise reflexes generated by moving limbs are important for triggering the exercise tachypneic response.

摘要

运动性呼吸增强时，来自运动肢体的神经传入成分的作用已在犬类中进行了研究。通过背根切断术和肢体交叉循环来评估神经和体液效应的影响。2. 在麻醉的犬类中，对其进行轻度电诱导运动（刺激L6或L7的腹根），在去传入神经前后分别测量呼吸分钟量（Ve）、频率（f）、潮气量（VT）和耗氧量（VO2）。3. 在对照实验中，呼吸分钟量（Ve）的增加与VO2成正比，且主要是由于频率的变化。在背根切断术（L1至S1）后，VO2增加，但其他呼吸参数未观察到显著变化。4. 与去传入神经实验相反，在交叉循环实验中，运动期间Ve或f均未检测到变化。5. 得出的结论是，在轻度运动期间，由运动肢体产生的反射对于触发运动性呼吸急促反应很重要。