DiNallo M C, Wohlford M, Van Houten J
Genetics. 1982 Oct;102(2):149-58. doi: 10.1093/genetics/102.2.149.
Ten mutant lines of Paramecium tetraurelia defective in attraction to folate were isolated and examined. All mutants were normal in response to other attractants and repellents tested. One mutant was able to accumulate in folate given sufficient time. All mutations were recessive and behaved as single site Mendelian lesions. Complementation tests indicate that the mutants fall into three complementation groups. Mutants of Group 2 fall into two phenotypic classes and probably represent two alleles of the mutated fol2 gene. Possible sites of the mutants' blocks in chemoresponse are discussed.
分离并检测了10株对叶酸缺乏吸引力的四膜虫突变株。所有突变株对测试的其他引诱剂和驱避剂反应正常。一个突变株在给予足够时间的情况下能够积累叶酸。所有突变均为隐性，表现为单基因座孟德尔损伤。互补试验表明，这些突变株分为三个互补群。第2组突变株分为两个表型类，可能代表突变的fol2基因的两个等位基因。讨论了突变株在化学感应中可能的阻断位点。
