Wilson T A
J Appl Physiol Respir Environ Exerc Physiol. 1982 Dec;53(6):1512-20. doi: 10.1152/jappl.1982.53.6.1512.
An energy analysis and data from the literature on the relation among surface area, recoil pressure, and lung volume are used to calculate the surface tension-surface area curves corresponding to pressure-volume loops. The energy analysis has been described earlier (J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 50: 921-926, 1981). It is based on the assumption that the tissue structure of the lung constitutes a conservative mechanical system and hence that pressure-volume hysteresis is primarily a result of surface tension-surface area hysteresis. Unlike previous methods of calculating surface tension from recoil pressure, this method does not rely on the assumption that the tissue component of recoil in the air-filled lung is the same as recoil pressure of the saline-filled lung at the same lung volume. The calculated values of surface tension decrease to less than 2 dyn/cm as surface area decreases along the deflation limb of the pressure-volume curve. Surface tension increases very steeply with surface area on the inflation limbs, reaching a limiting value of just under 30 dyn/cm. The shape of the surface tension-surface area curves, unlike the shape of the curves calculated by previous methods, is similar to the shape obtained on surface tension balances for fluid extracted from lungs.
利用能量分析以及文献中关于表面积、回缩压力和肺容积之间关系的数据，来计算与压力-容积环相对应的表面张力-表面积曲线。能量分析已在之前描述过（《应用生理学杂志：呼吸、环境与运动生理学》50: 921 - 926, 1981）。它基于这样的假设，即肺的组织结构构成一个保守的力学系统，因此压力-容积滞后主要是表面张力-表面积滞后的结果。与先前从回缩压力计算表面张力的方法不同，该方法不依赖于这样的假设：充气肺中回缩的组织成分与相同肺容积下充生理盐水肺的回缩压力相同。随着表面积沿压力-容积曲线的放气支减小，表面张力的计算值降至小于2达因/厘米。在充气支上，表面张力随表面积急剧增加，达到略低于30达因/厘米的极限值。表面张力-表面积曲线的形状与先前方法计算的曲线形状不同，类似于从肺中提取的液体在表面张力天平上得到的形状。
