[Retinal detachment and retraction. Effect of steroidal and nonsteroidal anti-inflammatory agents on the autoimmune reaction against the retina in idiopathic retinal detachment with signs of retraction].

The leukocyte adherence was employed to detect patients with auto-immunity against the retina, in three series of retinal detachments associated with peripheral vitreo-retinal retraction. The first serie of 14 patients received no medical treatment; the second serie of 19 patients was submitted an antiprostaglandins drug (tiaprofenic acid); the third serie of 16 patients received systemic corticoids. The leukocyte adherence test was performed before surgery and 10 days after surgery in all patients. It showed that auto-immunity against the retina after surgery was half as frequent in those patients submitted to anti-inflammatory drugs than in those patients who received no medical treatment. Moreover, the results of the present study suggest that: 1) Auto-immunity against the retina after surgery is twice as frequent in retinal detachments with associated massive vitreo-retinal retraction than in those which are surgical successes with good visual results (no macular pucker). 2) Auto-immunity against the retina 10 days after surgery is more frequent in those retinal detachments needing more than 20 cryo-applications than in those needing less than 20 cryo-applications.