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[采用简单胰岛素输注方案对不稳定型糖尿病患者进行调整]

[Adjustment of unstable diabetics with a simple insulin infusion program].

作者信息

Morell B, Blatter G, Froesch E R

出版信息

Schweiz Med Wochenschr. 1978 Nov 18;108(46):1803-6.

PMID:715417
Abstract

In view of the importance of knowing exactly how much insulin is required by diabetics who are difficult to control with subcutaneous insulin, an insulin infusion program has been tried in such patients. The apparatus, which was produced by Siemens as a prototype, works according to the following simple and flexible principle: During the day a basal rate of insulin is continuously infused. During the three main meals an additional rectangular insulin infusion is initiated by turning a knob. After an hour the apparatus switches automatically back to the basal ratio. We have used this machine in 13 patients who are fully mobile. 11 of them showed an almost ideal blood sugar profile after 4 days. After switching back to subcutaneous insulin 8 of these 11 patients did better than before but not as well as on the insulin infusion program.

摘要

鉴于准确了解皮下注射胰岛素难以控制血糖的糖尿病患者所需胰岛素剂量的重要性,已对这类患者试用了胰岛素输注方案。该装置由西门子作为原型生产,其工作原理简单且灵活:白天持续输注基础剂量的胰岛素。在三餐主餐期间,通过转动旋钮启动额外的矩形胰岛素输注。一小时后,装置自动切换回基础输注率。我们已在13名行动自如的患者中使用了这台机器。其中11名患者在4天后血糖水平几乎达到理想状态。在这11名患者换回皮下注射胰岛素后,其中8名患者的情况比之前有所改善,但不如使用胰岛素输注方案时好。

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