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[内科疾病中的碳水化合物输注。代谢健康者与肝病及糖尿病患者的对比研究。III. 48小时葡萄糖输注]

[Carbohydrate infusion in internal diseases. A comparative study of metabolically healthy persons and liver disease and diabetic patients. III. Glucose infusion over a 48-hour period].

作者信息

Müller P H, Egberts E H, Held W, Junger K, Schmülling R, Prestele H, Horbach L, Malchow H

出版信息

Infusionsther Klin Ernahr. 1981 Dec;8(6):266-9.

PMID:7035356
Abstract

6 metabolically healthy control persons, 6 patients with liver cirrhosis, and 6 patients with diabetes were infused for 48 hours with a 20 % (w/v) glucose solution. The infusion rate was 0,25 g glucose/kg body weight and hour. A constant surveillance of the metabolical status was performed by control of 39 different laboratory values. In all 3 groups, glucose infusion alone was sufficient for basal metabolic rate. This was shown by the inhibition of lipolysis as well as in the decreased catabolism. Only the diabetic group exhibited high blood-sugar values and an energy loss up to 10 % of the administered glucose. We could not observe any side effects.

摘要

6名代谢健康的对照者、6名肝硬化患者和6名糖尿病患者接受了48小时的20%(w/v)葡萄糖溶液输注。输注速率为0.25克葡萄糖/千克体重/小时。通过监测39项不同的实验室指标对代谢状态进行持续监测。在所有3组中,仅葡萄糖输注就足以满足基础代谢率。这通过脂解作用的抑制以及分解代谢的降低得以体现。只有糖尿病组出现高血糖值,且能量损失高达所输注葡萄糖的10%。我们未观察到任何副作用。

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