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[二尖瓣和主动脉瓣反流对左心室功能的影响]

[Effect of mitral and aortal regurgitation on the function of the left heart ventricle].

作者信息

Loviagin E V

出版信息

Kardiologiia. 1982 Nov;22(11):97-100.

PMID:7154516
Abstract

The paper is based on the data obtained through quantitative analysis of left cinoventriculograms and heart chamber catheterization in 136 patients with mitral and aortal regurgitation of the 2nd--4th degree. Left ventricular productivity was assessed on the basis of total stroke performance and capacity. Left ventricular productivity was found to be always increased in both kinds of regurgitation, irrespective of myocardial condition, and to increase further along with the increase in regurgitation volume. These hemodynamic parameters cannot be used for the assessment of myocardial contractility. In acquired valvular defects, myocardial contractility disorders may be diagnosed using the expulsion fraction, mean rate of muscular fibre shortening, relative mean expulsion rate and muscular contractility index as diagnostic parameters. The clinical value of contractility assessment is in that it can distinguish developing left ventricular failure from clinically similar symptom complexes and enables a more objective choice of treatment. Decreased myocardial contractility parameters in mitral and aortal regurgitation provide no counterindication for the correction of the defect.

摘要

本文基于对136例二至四级二尖瓣和主动脉瓣反流患者的左心室造影和心腔导管检查进行定量分析所获得的数据。左心室功能是根据总搏出量和能力来评估的。发现两种反流时左心室功能均总是增加,与心肌状况无关,并且随着反流体积的增加而进一步增加。这些血流动力学参数不能用于评估心肌收缩力。在获得性瓣膜缺损中,可使用射血分数、肌纤维平均缩短速率、相对平均射血速率和心肌收缩力指数作为诊断参数来诊断心肌收缩力障碍。收缩力评估的临床价值在于它可以将正在发展的左心室衰竭与临床相似的症状复合体区分开来,并能更客观地选择治疗方法。二尖瓣和主动脉瓣反流时心肌收缩力参数降低并不是纠正缺损的禁忌证。

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