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[氯丙嗪对肾上腺皮质酮分泌及垂体催乳素分泌的影响]

[Effect of chlorpromazine on adrenal secretion of corticosterone and pituitary secretion of prolactin].

作者信息

Lescoat G, Chambon Y

出版信息

J Pharmacol. 1982 Oct-Dec;13(4):535-42.

PMID:7154666
Abstract
  1. The authors studied, in adult male and female rats the effect of one or repeated injections of chlorpromazine on adrenal secretion of corticosterone and pituitary secretion of prolactin. 2. Injections of chlorpromazine increased plasma corticosterone, plasma and pituitary prolactin. 3. The discussion of the results was correlated to the brain catecholamines postulated to be neurotransmitters involved in the control of corticotropin and prolactin pituitary secretion.
摘要
  1. 作者研究了成年雄性和雌性大鼠单次或重复注射氯丙嗪对肾上腺皮质酮分泌及垂体催乳素分泌的影响。2. 注射氯丙嗪会增加血浆皮质酮、血浆和垂体催乳素水平。3. 对结果的讨论与假定为参与促肾上腺皮质激素和垂体催乳素分泌控制的神经递质的脑儿茶酚胺相关。

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1
[Effect of chlorpromazine on adrenal secretion of corticosterone and pituitary secretion of prolactin].[氯丙嗪对肾上腺皮质酮分泌及垂体催乳素分泌的影响]
J Pharmacol. 1982 Oct-Dec;13(4):535-42.
2
Adrenal influence on pituitary secretion of thyrotropin and prolactin in rats.肾上腺对大鼠垂体促甲状腺激素和催乳素分泌的影响。
Endocrinology. 1981 Apr;108(4):1545-51. doi: 10.1210/endo-108-4-1545.
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Indirect evidence to suggest that prolactin mediates the adrenal action of haloperidol to stimulate aldosterone and corticosterone secretion in rats.有间接证据表明，催乳素介导了氟哌啶醇对大鼠肾上腺的作用，以刺激醛固酮和皮质酮的分泌。
Endocrinology. 1992 Feb;130(2):914-9. doi: 10.1210/endo.130.2.1310283.
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D-Ala2-Met-enkephalinamide, a potent opioid peptide, alters pituitary-adrenocortical secretion in rats.D-丙氨酸2-甲硫氨酸脑啡肽酰胺，一种强效阿片肽，可改变大鼠垂体-肾上腺皮质的分泌。
Endocrinology. 1982 Nov;111(5):1483-90. doi: 10.1210/endo-111-5-1483.
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Effect of the growth hormone-secreting tumor StW5 on pituitary and adrenal gland function in rats.
Horm Res. 1981;14(1):36-46. doi: 10.1159/000179355.
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[Effect of chlorpromazine on pituitary concentrations of gonadotropins and prolactin in the pregnant rat].
Ann Endocrinol (Paris). 1983 Mar-Apr;44(2):127-9.
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Amplification of the corticotrophic action of arginine vasopressin during pituitary desensitization to corticotropin-releasing factor.垂体对促肾上腺皮质激素释放因子脱敏期间精氨酸加压素促肾上腺皮质激素作用的增强。
Pharmacol Res Commun. 1988 May;20(5):431-2. doi: 10.1016/s0031-6989(88)80028-6.
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[Disorder of catecholamine synthesis in early ontogeny and hypophyseal-adrenal cortical function in adult rats].
Ontogenez. 1984 May-Jun;15(3):327-31.
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Effects of neuropeptides B and W on the rat pituitary-adrenocortical axis: in vivo and in vitro studies.神经肽B和W对大鼠垂体-肾上腺皮质轴的影响：体内和体外研究
Int J Mol Med. 2007 Feb;19(2):207-11.
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Functional evaluation of prolactin secretion: a guide to therapy.催乳素分泌的功能评估：治疗指南。
J Clin Invest. 1972 Mar;51(3):706-9. doi: 10.1172/JCI106859.