Hejka Z, Kuncewicz T, Borowska-Lehman J
Neurol Neurochir Pol. 1982(5-6):363-9.
On the basis of clinical analysis and pathological findings in 25 patients dying after occlusion of the basilar artery the authors describe the main signs and course of the disease. Their observations made possible isolation of two types of the disease: 1) acute, with sudden consciousness disturbances leading to gradually increasing coma with flaccid extremities or decerebrate rigidity, stiff pupils not reacting to light and, frequently, with divergent squint, 2) subacute--with headache and hemiparaesthesiae and later quadriparesis and paresis of cranial nerves III to VII or IX, X, XII. A characteristic clinical feature is variability of neurological signs in the disease. The most frequent cause of basilar artery occlusion were atherosclerotic changes.
基于对25例基底动脉闭塞后死亡患者的临床分析和病理检查结果,作者描述了该病的主要体征和病程。他们的观察使得区分出两种类型的疾病成为可能:1)急性型,突发意识障碍,逐渐发展为昏迷,肢体松弛或出现去大脑强直,瞳孔固定、对光无反应,且常伴有外斜视;2)亚急性型,表现为头痛和偏身感觉异常,随后出现四肢瘫以及动眼神经、滑车神经、三叉神经、展神经、面神经、位听神经、舌咽神经、迷走神经及舌下神经麻痹。该病的一个典型临床特征是神经系统体征的多变性。基底动脉闭塞最常见的病因是动脉粥样硬化病变。