Rayburn W F, Motley M E, Stempel L E, Gendreau R M
Obstet Gynecol. 1982 Aug;60(2):148-53.
A prospective investigation was undertaken to determine whether present antepartum methods of fetal assessment were useful in predicting postmaturity. Thirty-two (22%) of 147 strictly defined postdate pregnancies produced infants with signs of postmaturity. Clinical findings, fetal heart rate testing (primarily nonstress tests), and fetal movement charting were not found to be reliable predictors. Single-voiding estrogen:creatinine (E:C) ratios were significantly (P less than .0001) lower in fetuses with subsequent findings of postmaturity than in those without such signs, and all subnormal values were associated with postmature infants. Twenty-four of 29 pregnancies with oligohydramnios diagnosed by ultrasonography produced postmature infants, whereas 110 of 118 pregnancies with either pockets or an adequate volume of amniotic fluid produced infants who were not postmature. Of the fetal surveillance methods used in the authors' clinic, subnormal E:C ratios and ultrasonic evidence of oligohydramnios were the most reliable predictors of postmaturity.
开展了一项前瞻性调查，以确定当前产前胎儿评估方法是否有助于预测过熟儿。在147例严格界定的过期妊娠中，有32例（22%）产出有过熟体征的婴儿。未发现临床检查结果、胎儿心率检测（主要是无应激试验）和胎动计数是可靠的预测指标。单次排尿雌激素与肌酐（E:C）比值在随后出现过熟体征的胎儿中显著（P<0.0001）低于无此类体征的胎儿，且所有低于正常的值均与过熟儿相关。超声诊断为羊水过少的29例妊娠中有24例产出过熟儿，而羊水有池或羊水量充足的118例妊娠中有110例产出非过熟儿。在作者诊所使用的胎儿监测方法中，E:C比值低于正常和羊水过少的超声证据是过熟最可靠的预测指标。
