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无应激试验与围产期结局。

Nonstress testing and perinatal outcome.

作者信息

Rayburn W, Greene J, Donaldson M

出版信息

J Reprod Med. 1980 May;24(5):191-6.

PMID:7401050
Abstract

The clinical value of nonstress testing (NST) in assessing fetal well-being is controversial. This study reviews the monitored tracings and subsequent perinatal outcome of 561 high-risk clinic patients who had undergone NST within one week prior to delivery. Two or more adequate accelerations of the fetal heart rate baseline with sufficient fetal activity over a 20-minute period were associated with a low risk of fetal jeopardy and were classified as a reactive test result. The corrected perinatal mortality of patients with reactive NSTs (1/509) was comparable to that of patients with no apparent antepartum complications (6/1,408) and was significantly lower (p less than 0.05) than those of high-risk patients with either nonreactive NSTs (2/22) or no testing (20/1,000). The incidence of subsequent perinatal jeopardy was significantly lower (p less than 0.001) among those high-risk pregnancies with recent reactive NST results (4%) than in those with recent nonreactive NST results (36%) and those without recent testing (13%). Perinatal morbidity among those pregnancies with recent reactive NSTs usually arose in the intrapartum period, and no reason to explain this jeopardy predominated. A reactive NST can be safely repeated in seven days, regardless of the adequately treated maternal risk factor. The only stillbirth following a reactive NST (1/509) probably arose from a cord accident.

摘要

无应激试验(NST)在评估胎儿健康状况方面的临床价值存在争议。本研究回顾了561例高危门诊患者在分娩前一周内接受NST的监测记录及随后的围产期结局。在20分钟内,胎儿心率基线有两次或更多次足够的加速且伴有足够的胎儿活动,与胎儿窘迫风险低相关,并被分类为反应型试验结果。反应型NST患者的校正围产期死亡率(1/509)与无明显产前并发症患者的死亡率(6/1408)相当,且显著低于无反应型NST(2/22)或未进行检测(20/1000)的高危患者(p<0.05)。近期NST结果为反应型的高危妊娠中,随后发生围产期窘迫的发生率(4%)显著低于近期NST结果为无反应型(36%)和未进行近期检测(13%)的高危妊娠(p<0.001)。近期NST结果为反应型的妊娠中,围产期发病率通常发生在产程中,且没有主要原因可解释这种窘迫。无论母体危险因素是否得到充分治疗,反应型NST均可在7天内安全重复进行。唯一一例反应型NST后的死产(1/509)可能是由脐带意外引起的。

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