Landrieu P, François B, Lyon G, Van Hoof F
Pediatr Res. 1982 Dec;16(12):977-81. doi: 10.1203/00006450-198212000-00001.
A boy with ornithine transcarbamylase (OTC) deficiency was relatively symptom free for 9 months and then developed an acute episode with liver failure and metabolic imbalance. Subsequently there was severe cerebral atrophy. Liver ornithine transcarbamylase activity was 3% of the normal mean. Of considerable interest was the finding of an accelerated breakdown of liver peroxisomes during the acute phase.
一名患有鸟氨酸转氨甲酰酶（OTC）缺乏症的男孩在9个月内相对无症状，随后出现了伴有肝功能衰竭和代谢失衡的急性发作。随后出现了严重的脑萎缩。肝脏鸟氨酸转氨甲酰酶活性为正常平均值的3%。在急性期发现肝脏过氧化物酶体加速分解，这一发现颇受关注。
