Bohe M, Lindström C, Ekelund G, Leandoer L
Scand J Gastroenterol. 1982 Sep;17(6):795-800. doi: 10.3109/00365528209181096.
A 20-year retrospective study of all anal canal carcinomas in the city of Malmö has been performed. The series consists of 29 patients, 23 women and 6 men, with a mean age of 66 years. Eight patients had non-keratinizing squamous cell carcinoma, 7 had keratinizing squamous cell carcinoma, 12 had basaloid squamous cell carcinoma, and 2 patients had mucoepidermoid carcinoma. Two of four patients operated on for curative purposes with local excision survived 5 years, as did seven of nine patients operated on curatively with abdominoperineal resection. In discussing the results, an overview of the literature is presented. It is concluded that adjuvant combined chemotherapy and radiotherapy appears to result in a higher survival rate for patients with tumours growing at or above the dentate line.
对马尔默市所有肛管癌进行了一项为期20年的回顾性研究。该系列包括29名患者,23名女性和6名男性,平均年龄为66岁。8例为非角化鳞状细胞癌,7例为角化鳞状细胞癌,12例为基底样鳞状细胞癌,2例为黏液表皮样癌。4例接受局部切除以达到根治目的的患者中有2例存活了5年,9例接受腹会阴联合切除以达到根治目的的患者中有7例存活了5年。在讨论结果时,对文献进行了综述。得出的结论是,辅助性联合化疗和放疗似乎能提高齿状线及以上部位肿瘤患者的生存率。