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[职业性接触苯的长期影响的纵向研究]

[Longitudinal study of the long-term effects of occupational exposure to benzene].

作者信息

Grossenbacher J, Lob M

出版信息

Schweiz Med Wochenschr. 1982 Dec 11;112(50):1858-9.

PMID:7156970
Abstract

A follow-up study has been conducted of 60 workers occupationally exposed to benzene for a period of 2 months to 19 years. Duration of the study was 18 years. All subjects were traceable. Ten deaths were recorded, four due to malignancies. No leukemia was observed. Increase of hemoglobin, platelets, white cells, neutrophils, lymphocytes and decrease of monocytes were observed between 1960-1964 and 1980, a fact which suggest a slight initial hematologic disorder in relation to benzene exposure which returned to normal thereafter.

摘要

对60名职业性接触苯2个月至19年的工人进行了一项随访研究。研究持续时间为18年。所有受试者均可追踪。记录到10例死亡,其中4例死于恶性肿瘤。未观察到白血病。1960年至1964年与1980年期间观察到血红蛋白、血小板、白细胞、中性粒细胞、淋巴细胞增加,单核细胞减少,这一事实表明与苯接触有关的轻微初始血液学紊乱,此后恢复正常。

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[Longitudinal study of the long-term effects of occupational exposure to benzene].[职业性接触苯的长期影响的纵向研究]
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引用本文的文献

1
Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice.苯在Fischer 344大鼠和B6C3F1小鼠中的多部位致癌性。
Environ Health Perspect. 1989 Jul;82:125-63. doi: 10.1289/ehp.8982125.