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废弃铅锌矿开采与冶炼地区的肺癌高发情况。

Lung cancer excess in an abandoned lead-zinc mining and smelting area.

作者信息

Neuberger J S, Hollowell J G

出版信息

Sci Total Environ. 1982 Nov;25(3):287-94. doi: 10.1016/0048-9697(82)90021-3.

DOI:10.1016/0048-9697(82)90021-3
PMID:7156973
Abstract

Analysis of cancer mortality in whites has revealed a significant excess in both males and females in an old lead/zinc mining and smelting area. This area consists of three rural contiguous counties: Cherokee County, Kansas, Jasper County, Missouri, and Ottawa County, Oklahoma. The lung cancer excess has persisted for at least 28 years for males and 5 years for females. A pilot case/control study is underway in Cherokee County to assess the influence of cigarette smoking, occupation, and residence on the lung cancer excess. Analysis will incorporate the histologic findings. From an environmental perspective, there are numerous mine tailings containing lead, zinc, cadmium, sulfur, germanium, and other chemicals. Considerable dust is airborne. Numerous openings (sink holes and bore holes) connect the old mines with the surface. Radium 226 has been detected in the untreated groundwater.

摘要

对白人癌症死亡率的分析显示,在一个旧的铅锌矿开采和冶炼地区,男性和女性的死亡率都显著偏高。该地区由三个相邻的农村县组成:堪萨斯州的切罗基县、密苏里州的贾斯珀县和俄克拉荷马州的渥太华县。男性肺癌死亡率偏高的情况至少持续了28年,女性则至少持续了5年。切罗基县正在进行一项初步的病例对照研究,以评估吸烟、职业和居住环境对肺癌死亡率偏高的影响。分析将纳入组织学检查结果。从环境角度来看,有大量含有铅、锌、镉、硫、锗和其他化学物质的矿渣。空气中弥漫着大量灰尘。许多开口( sink holes和钻孔)将旧矿井与地表相连。未经处理的地下水中检测到了镭226 。

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Potential health impacts of heavy-metal exposure at the Tar Creek Superfund site, Ottawa County, Oklahoma.俄克拉荷马州渥太华县塔尔溪超级基金污染场地重金属暴露对健康的潜在影响。
Environ Geochem Health. 2009 Feb;31(1):47-59. doi: 10.1007/s10653-008-9154-0. Epub 2008 Feb 28.
3
Implications of new data on lead toxicity for managing and preventing exposure.铅毒性新数据对管理和预防暴露的启示。
Environ Health Perspect. 1990 Nov;89:49-54. doi: 10.1289/ehp.908949.