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[不同血清组分对L细胞分化的影响]

[Effect of various serum fractions on L-cell differentiation].

作者信息

Shuklinov V A, Shumilina V V

出版信息

Tsitologiia. 1982 Dec;24(12):1454-8.

PMID:7157474
Abstract

It has been shown that the accumulation of lipids and maturation of L strain cells into mature lypocytes can be stimulated by high doses (30-60 mg/ml) of serum albumins, egg albumin lysozyme, and gelatin, or with low doses (200-600 mcg/ml) of serum globulins. The globulins are believed to induce differentiation of the L cell on depressing their proliferation. On the contrary, the low doses of albumins stimulate cell division without inducing differentiation.

摘要

已经表明,高剂量(30 - 60毫克/毫升)的血清白蛋白、蛋清溶菌酶和明胶,或低剂量(200 - 600微克/毫升)的血清球蛋白可刺激脂质积累以及L株细胞成熟为成熟淋巴细胞。据信球蛋白通过抑制L细胞增殖来诱导其分化。相反,低剂量的白蛋白刺激细胞分裂而不诱导分化。

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