Aberle H G, Horst W
Strahlentherapie. 1978 Nov;154(11):739-44.
Hundred patients with seminoma were irradiated in our clinic between 1963 and 1975. The 5-year survival rate corresponds to the rate of freedom from disease. It amounts to 97% for Stage I, 84% for Stage II, 55% for Stage III, O for Stage IV, and to 85% for all stages. These results are obtained by means of consequent radiation therapy. It is not cleared up wether general prophylactic irradiation improves the prognosis of mediastinal and supraclavicular affections. No complications may be expected on account of therapeutic doses, as the sensitivity to radiation is high. It is possible, on these grounds, in generalized stages, to take into consideration the total-body irradiation with low doses as an alternative to chemotherapy.
1963年至1975年间,我院对100例精原细胞瘤患者进行了放射治疗。5年生存率与无病生存率相当。I期为97%,II期为84%,III期为55%,IV期为0,所有阶段综合为85%。这些结果是通过连续放射治疗获得的。目前尚不清楚全身预防性照射是否能改善纵隔和锁骨上病变的预后。由于对辐射的敏感性较高,因此预计治疗剂量不会引起并发症。基于这些理由,在疾病广泛播散阶段,可以考虑采用低剂量全身照射作为化疗的替代方案。