Koivula A, Kauppila A, Kiviniitty K, Korhonen M, Vuopala S
Strahlentherapie. 1978 Nov;154(11):786-90.
Nuclear magnetic relaxation times T1 and T2 of cell water protons in benign and malignant uterine cervical tissue (37 samples taken from 22 patients) were measured using a resonance frequency of 19.8 MHz. The means of relaxation times recorded for malignant tissue were (mean +/- S.E.) T1 = 0.89 +/- 0.05 s, T2 = 0.072 +/- 0.009 s, and obtained from corresponding benign tissues (mean +/- S.E.) T1 = 0.72 +/- 0.01 s T2 = 0.056 +/- 0.003 s. The differences are statistically significant (T1:p less than 0.001, and T2:p less than 0.05). The effect of dysplasia and inflammatory changes in mucosa to the relaxation times were examined and the probable sources of error in the present method are discussed.
利用19.8MHz的共振频率测量了良性和恶性子宫颈组织（取自22例患者的37个样本）中细胞水质子的核磁共振弛豫时间T1和T2。记录的恶性组织弛豫时间平均值为（平均值±标准误）T1 = 0.89±0.05秒，T2 = 0.072±0.009秒，相应良性组织的弛豫时间平均值为（平均值±标准误）T1 = 0.72±0.01秒，T2 = 0.056±0.003秒。差异具有统计学意义（T1：p<0.001，T2：p<0.05）。研究了黏膜发育异常和炎症变化对弛豫时间的影响，并讨论了本方法可能存在的误差来源。
