Kautto U M, Heinonen J
Acta Anaesthesiol Scand. 1982 Dec;26(6):599-602. doi: 10.1111/j.1399-6576.1982.tb01823.x.
Circulatory responses to laryngoscopy and endotracheal intubation were compared between three groups of patients, two of which were subjected to a procedure of topical anaesthesia before induction of general anaesthesia. Topical anaesthesia, achieved with either a lidocaine dose aerosol or by gargling with viscous lidocaine, attenuated the magnitude of the pressor response to laryngoscopy and intubation but had no effect on the heart rate response. Lidocaine aerosol had some advantages over viscous lidocaine; these were the significantly smaller haemodynamic response to the local anaesthetic procedure itself and probably shorter duration of the circulatory changes produced by intubation. It is concluded that both of these simple methods are relatively ineffective in preventing haemodynamic changes associated with laryngoscopy and intubation and should probably be combined with another preventive method.
比较了三组患者对喉镜检查和气管插管的循环反应，其中两组在全身麻醉诱导前接受了局部麻醉 procedure。通过利多卡因剂量气雾剂或用粘性利多卡因漱口实现的局部麻醉减弱了对喉镜检查和插管的升压反应幅度，但对心率反应没有影响。利多卡因气雾剂比粘性利多卡因有一些优势；这些优势包括对局部麻醉 procedure 本身的血流动力学反应明显较小，以及插管产生的循环变化持续时间可能较短。得出的结论是，这两种简单方法在预防与喉镜检查和插管相关的血流动力学变化方面相对无效，可能应与另一种预防方法结合使用。
