Debski B
Acta Physiol Pol. 1982 Jan-Apr;33(1-2):83-90.
The investigation concerned the influence of ammonia ion on fresh sheep erythrocytes incubated in a buffer containing glucose, phosphate and adenosine. It was observed that the addition of NH4Cl to sheep erythrocytes increased their glucose metabolism which was manifested in an increase of glucose uptake and lactate production and also a higher Hx, G-6-PD and LHD activity. The author suggests that the influence of the ammonia ion on sheep erythrocytes may be responsible for higher glucose transport across the cell membrane of sheep erythrocytes which, in turn, is a result of increased ATP concentration in these cells. GSH concentration and per cent content of methaemoglobin in the erythrocytes did not change markedly in this experiment. An increase in the energy level of the erythrocytes (ATP/ADP + AMP) and 2,3 DPG concentration was observed which may have a significant influence on the amount of oxygen released by the erythrocytes in the tissues.
该研究关注铵离子对在含有葡萄糖、磷酸盐和腺苷的缓冲液中孵育的新鲜绵羊红细胞的影响。观察到向绵羊红细胞中添加氯化铵会增加其葡萄糖代谢，这表现为葡萄糖摄取和乳酸生成增加，同时己糖激酶、葡萄糖-6-磷酸脱氢酶和乳酸脱氢酶活性也更高。作者认为，铵离子对绵羊红细胞的影响可能是导致绵羊红细胞细胞膜上葡萄糖转运增加的原因，而这又是这些细胞中ATP浓度升高的结果。在该实验中，红细胞中的谷胱甘肽浓度和高铁血红蛋白的百分比含量没有明显变化。观察到红细胞的能量水平（ATP/ADP + AMP）和2,3-二磷酸甘油酸浓度增加，这可能对红细胞在组织中释放的氧量有显著影响。
