Moriette G, De Gamarra E, Cukier-Hemeury F, Murat I, Bordarier C, Relier J P
Arch Fr Pediatr. 1982 Oct;39(8):587-93.
70 neonates with birth weights (BW) less than 1 250 g were treated at the intensive care unit for neonates (USINN), hôpital Port-Royal, from April 1st 1976 to July 31st 1977. 16 of them had intra-uterine growth retardation. In 20, BW cas under 1 000 g. Assisted ventilation was necessary in 54 (77%). 43 children (61%) survived, those who were born in the same hospital did so more often (88%) than those who came from other hospitals (53%) (p less than 0.01). These results show the needs and risks of the management of very low birth weight neonates: preventing hypothermia, assisted ventilation of long duration and risk of persisting ductus arteriosus, prolonged parenteral nutrition, risk of intracranial hemorrhage more especially as respiratory distress is more severe. In survivors, the high rate of respiratory sequellae (around 30%) suggests that the duration and intensity of assisted ventilation should be reduced as much as possible.
1976年4月1日至1977年7月31日期间，70名出生体重（BW）低于1250克的新生儿在皇家港医院新生儿重症监护病房（USINN）接受治疗。其中16名患有宫内生长迟缓。20名新生儿出生体重低于1000克。54名（77%）需要辅助通气。43名儿童（61%）存活，在同一家医院出生的儿童存活率更高（88%），高于来自其他医院的儿童（53%）（p小于0.01）。这些结果显示了极低出生体重新生儿管理的需求和风险：预防体温过低、长时间辅助通气以及动脉导管未闭的风险、长期肠外营养、尤其是在呼吸窘迫更严重时颅内出血的风险。在幸存者中，较高的呼吸后遗症发生率（约30%）表明应尽可能减少辅助通气的持续时间和强度。
