Kelley J L, Wang C S, Bass H B, Thayer R H
Artery. 1982;10(6):379-94.
Lipoprotein lipase activity was measured in heparin extracts of aortic intima and adventitia from normal and cholesterol-fed turkeys. This lipolytic activity showed typical characteristics of lipoprotein lipase i.e., requirement of serum for activity and a 92% inhibition by protamine sulfate. The highest lipoprotein lipase activity was found in the adventitia of the abdominal aorta. Lipoprotein lipase activity was greater in the intima of the thoracic aorta than in the intima of the abdominal aorta. This higher activity of thoracic intima was not correlated with development of fibrous plaques which were found only in abdominal aorta. Cholesterol-feeding resulted in plasma very low density lipoproteins enriched in cholesterol-ester but had no effect on the level of lipoprotein lipase activity of aortic intima. Cholesterol-feeding, although altering lipoprotein composition, did not increase aortic intima lipoprotein lipase activity.
在正常和喂食胆固醇的火鸡的主动脉内膜和外膜的肝素提取物中测量了脂蛋白脂肪酶活性。这种脂解活性表现出脂蛋白脂肪酶的典型特征，即活性需要血清且被硫酸鱼精蛋白抑制92%。在腹主动脉外膜中发现了最高的脂蛋白脂肪酶活性。胸主动脉内膜中的脂蛋白脂肪酶活性高于腹主动脉内膜中的。胸内膜的这种较高活性与仅在腹主动脉中发现的纤维斑块的形成无关。喂食胆固醇导致血浆中富含胆固醇酯的极低密度脂蛋白增加，但对主动脉内膜脂蛋白脂肪酶活性水平没有影响。喂食胆固醇虽然改变了脂蛋白组成，但并未增加主动脉内膜脂蛋白脂肪酶活性。
