Santiago M F, Bassi G E
Arq Neuropsiquiatr. 1982 Sep;40(3):276-80. doi: 10.1590/s0004-282x1982000300010.
The authors make a literature review about the meningeal involvement in MM and verified that the presence of myeloma cells in the CSF is rare. They report a case of cranial MM in which the atypical plasma cells (plasmoblasts) were present in CSF. The CSF examination was the principal finding to the diagnosis of this case; it was confirmed by IgG monoclonal "M" gamophaty present in serum, CSF and urine obtained through proteic electrophoresis profile and by necropsy that revealed mielomatous proliferation in skull base with subarachnoidal space infiltration.
作者对多发性骨髓瘤（MM）的脑膜受累情况进行了文献综述，并证实脑脊液（CSF）中存在骨髓瘤细胞的情况较为罕见。他们报告了一例颅骨MM病例，其中CSF中存在非典型浆细胞（成浆细胞）。CSF检查是该病例诊断的主要依据；通过蛋白质电泳图谱在血清、CSF和尿液中发现的IgG单克隆“M”蛋白血症以及尸检显示颅底骨髓瘤增殖伴蛛网膜下腔浸润，均证实了该诊断。
