Takigawa M, Taira N, Sameshima S
No To Shinkei. 1982 Nov;34(11):1085-90.
Formation of the secondary focus in the rabbit amygdala Kindling (K) phenomenon was analysed by the coherence method. This method is capable of showing the degree of correlation between two signals (EEG) at each frequency. Mature male rabbits were used and a train stimulation using a biphasic square wave of 60 Hz was applied to the amygdala for two second once a day until the completion of K-phenomenon. The results obtained were as follows. 1) The coherence values between the amygdaloid K-region and opposite amygdala were usually much higher than those of the cerebral cortex (motor and optic areas) with a frequency of 6 to 7 Hz before and after completion of the K-phenomenon. 2) The speed of the secondary focus formation was observed to be parallel with the coherence value. 3) The secondary focus formation induced by the K of amygdala in a rabbit has much to do with the 6 Hz nerve circuit which links between the primary focus and secondary focus. That is, if the coherence value appears high around 6 Hz, the secondary focus is easily formed in case of a rabbit. 4) Application of this method enabled us to see the degree of functional correlation between the primary focus and secondary focus at each frequency. With all these, it is suggested that the theta frequency ranges of power spectra between above region play a vital role in producing secondary focus formation of the amygdaloid Kindling in rabbits.
用相干分析法分析家兔杏仁核点燃（K）现象中次级灶的形成。该方法能够显示两个信号（脑电图）在每个频率下的相关程度。选用成年雄性家兔，每天一次对杏仁核施加60赫兹双相方波串刺激，持续两秒，直至K现象完成。得到的结果如下：1）在K现象完成前后，杏仁核K区与对侧杏仁核之间的相干值通常远高于大脑皮层（运动区和视区），频率为6至7赫兹。2）观察到次级灶形成的速度与相干值平行。3）家兔杏仁核K诱导的次级灶形成与连接初级灶和次级灶的6赫兹神经回路密切相关。也就是说，如果在6赫兹左右相干值较高，家兔就容易形成次级灶。4）应用该方法能让我们看到初级灶和次级灶在每个频率下的功能相关程度。综上所述，上述区域之间功率谱的θ频率范围在产生家兔杏仁核点燃的次级灶形成中起着至关重要的作用。
