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Ganglioside changes during cell aging in human diploid fibroblast TIG-1.

作者信息

Ohsawa T, Nagai Y

出版信息

Exp Gerontol. 1982;17(4):287-93. doi: 10.1016/0531-5565(82)90018-3.

DOI:10.1016/0531-5565(82)90018-3
PMID:7160447
Abstract

Gangliosides of human diploid fibroblast, TIG-1, derived from fetal lung were analyzed during cell aging. The major gangliosides of TIG-1 cells were GM3 and GD3. During cell aging, GM3 and other gangliosides were decreased or below detection level. Lipid-bound sialic acid per mg protein was 2 micrograms at the early, middle and late passages, but between the middle and late passage it was twofold higher than the other passages.

摘要

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