Shapkin A G
Vestn Khir Im I I Grek. 1978 Oct;121(10):103-8.
Some experimental data concerning the pathogenesis of tuberculous injury to the kidneys have been obtained from a complex study of the microcirculatory blood bed on a model of tuberculosis of the kidneys in 112 rabbits. Clinical investigations and clinico-experimental correlations have provided pathogenetic grounds for a surgical method of the treatment of tuberculosis of the kidneys complicated with strictures or the ureter. The pathogenetic association of the main tuberculous focus in the renal parenchyma with the tuberculous injury to the ureter and perivascular expansion of specific infection has been pointed to. The effectiveness of pathogenetically grounded surgical intervention has been proved in 52 patients followed-up from 1.5 to 7 years.
通过对112只兔肾结核模型的微循环血床进行综合研究,已获得了一些关于肾结核损伤发病机制的实验数据。临床研究及临床与实验的相关性为治疗并发狭窄或输尿管结核的肾结核的手术方法提供了发病学依据。已指出肾实质内主要结核病灶与输尿管结核损伤及特异性感染的血管周围扩展之间的发病学关联。对52例随访1.5至7年的患者进行的研究证明了基于发病机制的手术干预的有效性。