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搏动性对人体动脉壁氧输送的影响。

Effect of pulsatility on oxygen transport to the human arterial wall.

作者信息

Schneiderman G, Mockros L F, Goldstick T K

出版信息

J Biomech. 1982;15(11):849-58. doi: 10.1016/0021-9290(82)90050-1.

DOI:10.1016/0021-9290(82)90050-1
PMID:7161287
Abstract

Oxygen transfer in fully-developed, pulsating, laminar flow in rigid and distensible tubes was simulated as part of a study of vessel-wall hypoxia and atherogenesis. The model used for the computations is based on dimensions and flows in the human thoracic aorta. The pulsatile velocity fields employed are based on those of Womersley with the modification that the radial convection is written relative to the moving wall. Womersley-type pulsatility, superposed on an axial Poiseuille flow, was found to negligibly affect oxygen transport to the wall. Caution should be exercised, however, in extending this conclusion to the complex pulsatility in actual living vessels.

摘要

作为对血管壁缺氧和动脉粥样硬化研究的一部分,对刚性和可扩张性血管中充分发展的脉动层流中的氧气传输进行了模拟。用于计算的模型基于人体胸主动脉的尺寸和血流。所采用的脉动速度场基于沃默斯利(Womersley)的速度场,并做了如下修正:径向对流是相对于移动壁面来描述的。人们发现,叠加在轴向泊肃叶流上的沃默斯利型脉动对向血管壁的氧气输送影响可忽略不计。然而,在将这一结论推广到实际活体血管中的复杂脉动时应谨慎。

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